- Electrolytes are charged ions that are essential for various physiological processes in the body. - Common electrolytes include sodium (Na+), potassium (K+), calcium (Ca2+), magnesium (Mg2+), chloride (Cl-), and bicarbonate (HCO3-). - These electrolytes are present in bodily fluids like blood, plasma, intracellular fluid, and extracellular fluid. - Sodium is the main extracellular positive ion, and it regulates fluid balance, nerve function, and muscle contractions. (Source: Verbalis, J. G. (2018). Disorders of Electrolyte Balance. In Harrison's Principles of Internal Medicine, 20e. McGraw-Hill Education.) - Potassium is the main intracellular positive ion and plays a crucial role in nerve impulse transmission and muscle function. (Source: Alpern, R. J., & Sakhaee, K. (2003). Renal regulation of body acid-base balance. In Seldin and Giebisch's The Kidney: Physiology and Pathophysiology (4th ed., pp. 2321–2378). Elsevier Science.) - Calcium is involved in muscle contraction, enzyme activation, and blood clotting. (Source: Boron, W. F., & Boulpaep, E. L. (2017). Medical Physiology: A Cellular and Molecular Approach (3rd ed.). Elsevier.) - Magnesium is necessary for energy production, protein synthesis, and nerve function. (Source: Swaminathan, R. (2003). Magnesium Metabolism and its Disorders. In Seldin and Giebisch's The Kidney: Physiology and Pathophysiology (4th ed., pp. 1655–1678). Elsevier Science.) - Chloride ions help maintain fluid balance, aid digestion, and assist in acid-base balance. (Source: Greenberg, A., & Mader, S. (2014). Acid-Base Disturbances. In Approach to Internal Medicine: A Resource Book for Clinical Practice (4th ed., pp. 213–229). Springer New York.) - Bicarbonate ions are important in maintaining acid-base balance, primarily acting as a buffer against pH changes. (Source: Lieberthal, W., & Levine, J. S. (2018). Electrolyte and Acid-Base Disorders. In Brenner and Rector's The Kidney (11th ed., pp. 214–235). Elsevier.)
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