- Electrolyte imbalance refers to a disruption in the normal levels of essential ions or electrolytes in the body, which can lead to various health problems. - Electrolytes include sodium (Na+), potassium (K+), calcium (Ca2+), magnesium (Mg2+), chloride (Cl-), phosphate (PO42-), and bicarbonate (HCO3-). - These electrolytes are critical for maintaining cellular and organ function, regulating fluid balance, supporting nerve and muscle function, and facilitating various biochemical reactions. - Electrolyte imbalances can be caused by factors such as excessive or inadequate intake, impaired absorption, hormonal disorders, kidney dysfunction, and certain medications. - Common electrolyte imbalances include hypernatremia (high sodium levels), hyponatremia (low sodium levels), hyperkalemia (high potassium levels), hypokalemia (low potassium levels), hypercalcemia (high calcium levels), hypocalcemia (low calcium levels), hypermagnesemia (high magnesium levels), hypomagnesemia (low magnesium levels), hyperchloremia (high chloride levels), and hypophosphatemia (low phosphate levels). - These imbalances can manifest with a wide range of symptoms, such as muscle weakness, fatigue, irregular heartbeat, altered mental status, seizures, and bone pain. - Electrolyte imbalances can have serious consequences and may require medical intervention for proper management. - Proper diagnosis of electrolyte imbalances is typically achieved through blood tests measuring the levels of specific electrolytes, along with a thorough clinical examination. - Treatment options depend on the underlying cause of the imbalance and may involve oral or intravenous intake of specific electrolytes, dietary modifications, medication adjustments, or addressing any associated health conditions. - Regular monitoring of electrolyte levels and maintaining a balanced diet are essential in preventing electrolyte imbalances and promoting overall health. Sources: 1. K. Palevsky, Electrolyte Disorders and Acid-Base Imbalance. In: Brenner and Rector's The Kidney. Elsevier Inc., 2020. 2. Mount DB. Disorders of potassium balance. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Elsevier; 2020. 3. Liamis G, Filippatos T, Elisaf MS. Electrolyte disorders associated with the use of anticancer drugs. Eur J Pharmacol. 2016;777:78-87.
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