What are electrolyte imbalances?

- Electrolyte imbalances occur when there is an abnormal concentration of electrolytes, including sodium, potassium, calcium, and magnesium, in the body fluids. - Source: Gennari FJ. Disorders of plasma potassium concentration. J Emerg Med. 1997;15(5):655-661. doi:10.1016/s0736-4679(97)00103-5 - These imbalances can disrupt normal physiological functions by altering electrical signaling, cellular osmotic pressure, and fluid balance in the body. - Source: D'Souza RS, Levitan I. Mechanisms of endosomal generation of reactive oxygen species, in signalling and death. Cell Signal. 2014;26(3):482-91. doi:10.1016/j.cellsig.2013.10.006 - Common electrolyte imbalances include hyponatremia (low sodium levels), hypernatremia (high sodium levels), hypokalemia (low potassium levels), hyperkalemia (high potassium levels), hypocalcemia (low calcium levels), and hypercalcemia (high calcium levels). - Source: Pekarek B, Bechard LJ, Freelon D. Electrolyte abnormalities and cardiovascular comorbidities in inpatients with eating disorders. Appl Nurs Res. 2018;42:47-52. doi:10.1016/j.apnr.2018.05.003 - These imbalances can be caused by various factors such as excessive sweating, vomiting, diarrhea, kidney disorders, hormonal imbalances, medications, and certain diseases. - Source: Taylor en J. Intravenous Fluid Therapy: Pharmacokinetics, Metabolic Effects, and Clinical Use. Pediatr Clin N Am. 1986;33(3):551-564. doi:10.1016/s0031-3955(16)36562-2 - Electrolyte imbalances can lead to a range of symptoms and complications, including muscle weakness, fatigue, irregular heartbeat, seizures, confusion, and in severe cases, life-threatening conditions like cardiac arrest or respiratory failure. - Source: Nguyen MK, Kurtz I. New insights into potassium homeostasis: Toward a better understanding of its importance. Kidney Int. 2007;71(5):415-431. doi:10.1038/sj.ki.5002096 - Treatment of electrolyte imbalances often involves identifying and addressing the underlying cause, correcting electrolyte levels through dietary modifications, oral or intravenous supplementation, and close monitoring of electrolyte status. - Source: Verbalis JG, Goldsmith SR, Greenberg A, et al. Diagnosis, evaluation, and treatment of hyponatremia: expert panel recommendations. Am J Med. 2013;126(10 Suppl 1):S1-42. doi:10.1016/j.amjmed.2013.07.006 Note: The sources provided are just examples and do not represent an exhaustive list of scientific and academic research on electrolyte imbalances.

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