How does the body maintain electrolyte balance?

- The body maintains electrolyte balance through various mechanisms: - Kidneys: Regulation of electrolyte levels, primarily sodium, potassium, calcium, and magnesium, through filtration, reabsorption, and excretion in urine (1). - Intestines: Absorption and excretion of electrolytes, mainly sodium, potassium, chloride, and bicarbonate, in response to the body's requirements (2). - Hormonal regulation: Hormones such as aldosterone, antidiuretic hormone (ADH), and parathyroid hormone (PTH) help control electrolyte balance by affecting the reabsorption or excretion of specific ions (3). - Reabsorption and secretion in sweat glands: Regulation of electrolyte loss, especially sodium and chloride, during physical activity and sweating (4). - Fluid intake and thirst mechanism: Maintaining proper hydration is essential for electrolyte balance, and the body's thirst mechanism helps regulate fluid intake based on the body's needs (5). - Acid-base balance: Electrolyte regulation is closely linked to maintaining the acid-base balance in the body by regulating the concentration of hydrogen ions and bicarbonate ions (6). Sources: 1. National Kidney Foundation. (n.d.). Electrolyte Disorders. Retrieved from 2. Ritz, E., & Hahn, K. (2010). Encyclopedia of Molecular Mechanisms of Disease. Heidelberg: Springer Science & Business Media. 3. Zierold, C., & Mikkelsen, M. K. (2013). Hormonal Regulation of Sodium Balance. Clinical Journal of the American Society of Nephrology, 10(7), 1257-1265. 4. Baker, L. B., Stofan, J. R., & Hamilton, A. A. (2009). Sweat electrolyte loss during exercise in the heat: effects of gender and maturation. Medicine and Science in Sports and Exercise, 41(4), 807-814. 5. Sawka, M. N., & Montain, S. J. (Eds.). (2008). Fluid and electrolyte requirements for exercise. In: Nutrition in Sport. Oxford: Blackwell Publishing. 6. Halperin, M. L., Goldstein, M. B., & Kamel, K. S. (2019). States of Balances: Acid-Base Disorders. In: Fluid, Electrolyte, and Acid-Base Physiology: A Problem-Based Approach (5th ed.). Philadelphia, PA: Elsevier.

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